Title: Endocrine / Physiology / pg334 Prolactin

Q: [...] is secreted mainly by [...]
A: Prolactin; anterior pituitary

Q: Which hormone is structurallly homologus to Prolactin ?
A: Growth hormone

Q: Prolactin [...] milk production in breast, [...] ovulation in females and spermatogenesis in males. (stimulates or inhibits)
A: stimulates; inhibits

Q: Excessive amounts of Prolactin is associated with which condition:
A: ↓ libido

Q: Prolactin secretion is regulated by:
A: Dopamine & TRH

Prolactin is inhibited  by Dopamine and stimulated by TRH

Q: What is the treatment of Prolactinoma (Excessive secretion of Prolactin) ?
A: Dopamine agonists (eg, bromocriptine, cabergoline)

Q: How can we stimulate prolactin secretion ?
A: - Dopamine antagonists (most antipsychotics, metoclopramide)
- estrogens (OCPs, pregnancy)

- Prolactin is regulated by Dopamine and TRH
- Cry of baby stimulates Prolactin

Q: examples on Dopamine agonists:
A: 1. bromocriptine
2. cabergoline